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Fluorescence microscope including normal fluorescent staining and immunofluorescence staining. The normal fluorescence staining can show different content inside the cell, especially show the specificity of DNA or RNA, and acid mucopolysaccharide clearly. The immunofluorescence staining combine the advantage of immunological technique and fluorescence staining together, it is widely used in all kinds of basic theories research and clinical diagnosis, like histocytology, microbiology, parasitology, pathology and autoimmune disease diagnosis.