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Mattioli Dermoelectroporation®, technology is consolidated to be an incredible procedure that allows the transdermal delivery of whatever substance operators want, which are otherwise not absorbed into the skin because of the typology and dimension of their own molecules. Dermoelectroporation® infact, increases the skins permeability just using some skin's water based channels opened by a particular controlled current delivered to the patient and allowing the substances to absobed till hypodermis and muscle membranes. The system has been FDA approved for the local administration of onic drug solutions into the body for medical purposes and can be used as an alternative to injections. DEP SYSTEM IS MADE OF THE FOLLOWING DEVICES: Power supply and control base DEP Transdermal delivery handpiece with Super Precision Liquid Dispenser - Super PLD. Macromolecules (such as Hyaluronic Acid) previously not transdermally deliverable by traditional Ionthophoresis are now successfully deliv