Injectable Tetracaine Hydrochloride Powder 99% for Local Anesthesia
2016-09-12 11:26  Views:180
Price:10.00 USD/Bags
Brand:SC
Model:Tetracaine
MOQ:1 Bags
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keywords:
Tetracaine hydrochloride ;
Injectable;
Local anesthesia;
 

Product Name: Tetracaine hydrochloride
Synonyms: L AND OCAIN HYDROCHLORIDE;INTERCAIN HYDROCHLORIDE;MEETHOBALM HYDROCHLORIDE;2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE;2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE;4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE;4-[BUTYLAMINO]BENZOIC ACID-2-[DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE;4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL
CAS: 136-47-0
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
Product Categories: API intermediates;Sodium channel;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;PONTOCAINE;Local anesthetic
Mol File: 136-47-0.mol
Chemical Properties White Solid
Usage anesthetic (local)
Usage A local anesthetic used topically in opthalmology.


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Description:

Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an 
acid-catalyzed esterification reaction. base-catalyzed transesterification is achieved by boiling the ethyl 
ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount 
of sodium ethoxide.
 
Application:
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent
local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it 
has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine 
receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of 
channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium 
release events, while at high concentrations, tetracaine blocks release completely.

 
4.Related Local Anesthesia Powder:

Propitocaine hydrochloride CAS: 1786-81-8 
Tetracaine hydrochloride CAS: 136-47-0 
Procaine hydrochloride CAS: 51-05-8 
Pramoxine hydrochloride CAS: 637-58-1 
Proparacaine hydrochloride CAS: 5875-06-9 
Benzocaine hydrochloride CAS: 23239-88-5
Lidocaine hydrochloride CAS: 73-78-9 
Articaine hydrochloride CAS: 23964-57-0 
Levobupivacaine hydrochloride CAS: 27262-48-2 
Ropivacaine hydrochloride CAS: 132112-35-7 
Dibucaine hydrochloride CAS: 61-12-1
Bupivacaine hydrochloride CAS: 14252-80-3 
Articaine CAS: 23964-58-1 
Benzocaine CAS: 94-09-7
Lidocaine CAS: 137-58-6 
Tetracaine CAS: 94-24-6 
PROCAINE CAS: 59-46-1 
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