plasmapheresis method is to flow a patient's blood into the plasma exchange device, and discard the plasma containing a large number of isolated autoantibodies, immune complexes, plasma inflammatory pathogenic factors , and add some fresh plasma or substitutes, such as 4% human serum albumin, Ringer's solution, etc., to get rid of soluble immune complexes and some antibodies.   http://www.yumeiid.com/