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177036-94-1 Pulmonary Hypertension Anti Hypertensive Drugs Ambrisentan
| Name | Ambrisentan |
| Synonyms | 2-(4,6-Dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-di(phenyl)propanoic acid |
| Molecular Formula | C22H22N2O4 |
| Molecular Weight | 378.42 |
| CAS Registry Number | 177036-94-1 |
Description:
Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension.
The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor.Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials.
COMPANY INTRODUCTION:
Our company, as one of the most experienced exporter in China,specializes in API
and medicine intermediates. We export large quantity to USA,Europe and many other
countries all of the world, deal to high quality and reasonable price.
Patent Disclaimer:
1. Products protected by valid patents are not offered for sale in jurisdictions where the sale of such products constitutes a patent infringement. The current list only reflects the products and technologies that are available, under development: note that some products may be developed or produced for internal and experimental uses with no commercal aim.
2. Sales of products are limited to those allowed by Chapter VII PLPRC 63, the above includes Research and development quantities.
3. R&D use in accordance with (1) 35 USC 271(e)+A13(1) in the U.S.; (2) Section 69.1 of Japanese Patent Law in Japan; (3) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (4) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (5) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (6) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (7) such similar laws and rules as may apply in various other countries.




